Search results for "Repetition Time"

showing 5 items of 5 documents

Stronger proprioceptive BOLD-responses in the somatosensory cortices reflect worse sensorimotor function in adolescents with and without cerebral pal…

2020

Graphical abstract

CP-oireyhtymäCHILDRENSM1PASSIVE FINGERDP diplegic3124 Neurology and psychiatryEVOKED-POTENTIALSBRAINChildMOTOR CORTEXPassive movementTE echo timeEM expectation maximizationliikeaistiBOLD Blood-Oxygen-Level-Dependent signalRegular ArticleMagnetic Resonance ImagingTD typically-developedTR repetition timeSIIGMFCS Gross Motor Function Classification SystemMANCOVA Multivariate analysis of covarianceEPI echo planar imagingHP hemiplegicfMRI functional magnetic resonance imagingFemaleTACTILE STIMULATIONhalvausAGE-RELATED DIFFERENCESAdolescentComputer applications to medicine. Medical informaticsR858-859.7HemiplegiaORGANIZATIONDiplegiatuntoaistiMOVEMENTSIPT Sensory Integration and Praxis TestsROI regions of interestHumansSISII cortex secondary somatosensory cortexCP cerebral palsyRC346-429ComputingMethodologies_COMPUTERGRAPHICSGLM General Linear ModelCerebral Palsy3112 NeurosciencesSPM Statistical Parametric MappingSomatosensory CortexHandProprioceptionSI cortex primary somatosensory cortexGABA CONCENTRATIONKinesthesiaNeurology. Diseases of the nervous systemPSC percent signal change
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Increased cortical curvature reflects white matter atrophy in individual patients with early multiple sclerosis

2014

Objective White matter atrophy occurs independently of lesions in multiple sclerosis. In contrast to lesion detection, the quantitative assessment of white matter atrophy in individual patients has been regarded as a major challenge. We therefore tested the hypothesis that white matter atrophy (WMA) is present at the very beginning of multiple sclerosis (MS) and in virtually each individual patient. To find a new sensitive and robust marker for WMA we investigated the relationship between cortical surface area, white matter volume (WMV), and whole-brain-surface-averaged rectified cortical extrinsic curvature. Based on geometrical considerations we hypothesized that cortical curvature increa…

MalePathologyROI region of interestFOV field of viewlcsh:RC346-429ImagingGRAPPA generalized autocalibrating partially parallel acquisitionCortex (anatomy)Image Processing Computer-AssistedFA fractional anisotropyWMV white matter volumeTE echo timeCerebral Cortexmedicine.diagnostic_testEVAL Münster Neuroimaging Evaluation SystemMiddle AgedMagnetic Resonance ImagingWhite MatterTR repetition timemedicine.anatomical_structureNeurologyGMV gray matter volumeCerebral cortexCortexlcsh:R858-859.7FemaleAlzheimer's diseasePsychologyCIS clinically isolated syndromeMRITSE turbo spin-echoAdultmedicine.medical_specialtyAdolescentCognitive NeuroscienceCortical curvatureICV intracranial volumelcsh:Computer applications to medicine. Medical informaticsCurvatureArticleEDSS Expanded Disability Status ScaleMultiple sclerosisWhite matterYoung AdultAtrophyAlzheimer DiseasemedicineHumansRadiology Nuclear Medicine and imagingWM white matterlcsh:Neurology. Diseases of the nervous systemAgedMultiple sclerosis3D three-dimensionaleWMV estimated white matter volumeMagnetic resonance imagingmedicine.diseaseΔWMV WMV − eWMVCI confidence intervalCase-Control StudiesGM gray matterAnisotropyDTI diffusion tensor imagingNeurology (clinical)AtrophySD standard deviationDemyelinating DiseasesNeuroImage: Clinical
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Mathematical models for the diffusion magnetic resonance signal abnormality in patients with prion diseases

2014

In clinical practice signal hyperintensity in the cortex and/or in the striatum on magnetic resonance (MR) diffusion-weighted images (DWIs) is a marker of sporadic Creutzfeldt–Jakob Disease (sCJD). MR diagnostic accuracy is greater than 90%, but the biophysical mechanisms underpinning the signal abnormality are unknown. The aim of this prospective study is to combine an advanced DWI protocol with new mathematical models of the microstructural changes occurring in prion disease patients to investigate the cause of MR signal alterations. This underpins the later development of more sensitive and specific image-based biomarkers. DWI data with a wide a range of echo times and diffusion weightin…

MalePathologysCJD sporadic Creutzfeldt–Jakob diseaseROI region of interestPrion diseasePrPSc prion protein scrapieElectroencephalographyFOV field of viewlcsh:RC346-429Prion DiseasesADC apparent diffusion coefficientTI inversion timeRPE rapidly progressive encephalopathyAged 80 and overTE echo timeBrain Mappingmedicine.diagnostic_testBrainRegular ArticleMiddle AgedBIC Bayesian information criterionTR repetition timemedicine.anatomical_structureNeurologylcsh:R858-859.7FemaleMPRAGE magnetization-prepared rapid acquisition gradient-echoAbnormalitySS-SE single shot spin-echoAdultmedicine.medical_specialtyCognitive NeuroscienceCreutzfeldt–Jakob diseaseCNR contrast to noise ratioEPI echo-planar imagingNeuropathologyPrPC prion protein cellularGrey matterSpongiform degenerationlcsh:Computer applications to medicine. Medical informaticsEEG electroencephalogramDiffusion MRINeuroimagingImage Interpretation Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imaginglcsh:Neurology. Diseases of the nervous systemAgedCJD Creutzfeldt–Jakob diseaseGSS Gerstmann–Sträussler–Scheinker syndromebusiness.industryDWI diffusion weighted imagingDiffusion MRI; Biophysical models; Creutzfeldt-Jakob disease; Prion disease; Spongiform degenerationMagnetic resonance imagingModels TheoreticalHyperintensityCreutzfeldt-Jakob diseaseDiffusion Magnetic Resonance ImagingNeurology (clinical)businessBiophysical modelsDiffusion MRINeuroImage: Clinical
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A multicenter measurement of magnetization transfer ratio in normal white matter

1999

To assess the importance of intercenter variations when measuring magnetization transfer ratio (MTR) in the brain, six European centers measured MTR in normal white matter. MTR ranged from 9 to 51 percent units (25 sequences). The effective flip angle of the saturating pulse divided by the pulse repetition time (ENRsat degrees/msec) was a good predictor of MTR (MTR = 3.25 ENRsat).

PhysicsDrug trialMagnetization Transfer MRIbusiness.industryWhite mattermedicine.anatomical_structureRepetition TimeFlip anglemedicineBrain mriRadiology Nuclear Medicine and imagingMagnetization transferNuclear medicinebusinessJournal of Magnetic Resonance Imaging
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MRI of inner ear fluids using modified GRASS sequences: a useful tool in the assessment of the normal and pathological labyrinth

1995

MRI is acquiring a progressively more important role in the investigation of petrous bone disease. Nevertheless, despite the extensive use of MRI in the detection of inflammatory or neoplastic involvement of the seventh and eighth cranial nerves, conventional spinecho images cannot be considered the modality of choice in inner ear imaging “Steady-state sequences” are known to be motion sensitive. By setting a very short repetition time, a large flip angle and a long echo time, one can obtain a sequence sufficiently sensitive to the slow movement of endo- and perilymph. We report our experience in MRI of normal and pathological inner ear with modified GRASS sequences.

medicine.diagnostic_testEcho timeCranial nervesMagnetic resonance imagingAnatomyBiologyPerilymphmedicine.anatomical_structureRepetition TimeFlip angleotorhinolaryngologic diseasesmedicineInner earsense organsPathological
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